1877-1894: Dr. Charles Ayer
1894-1911: Dr. Luther G. Barrett
1911-1927: Dr. Zachary T. Hubert
1927-1940: Dr. B. Baldwin Dansby
1940-1967: Dr. Jacob L. Reddix
1967-1984: Dr. John A. Peoples, Jr.
1984-1991: Dr. James A. Hefner
1991-1992: Dr. Herman B. Smith, Jr. (interim)
1992-1999: Dr. James E. Lyons Sr.
1999-2000: Dr. Bettye Ward Fletcher (interim)
2000-2010: Dr. Ronald Mason, Jr.
2010: Dr. Leslie Burl McLemore (interim)
2011-2016: Dr. Carolyn W. Meyers
2016-2017: Dr. Rod Paige (interim)
2017-2020: Dr. William B. Bynum
2020-2023 Thomas Hudson
2023-present Elayne Hayes-Anthony